一名年轻女孩在大城市失踪了,神父於是铤而走险,找上恶魔猎人和他龙蛇混杂的手下帮忙,执行一项超自然的寻人任务。Diablero is centered around Father Ramiro Ventura, a fallen priest who finds himself seeking the aid of legendary "diablero" or demon hunter Elvis Infante. With the aid of Nancy Gama, a modern day superhero, this improbable trio sets in motion a series of events that could determine the fate of mankind.